Multimodal sensing methods have a great promise in biosensing applications as they can measure independently several properties that characterise the biomolecular interaction to be detected as well as providing inherent on-chip validation of the sensing signals. This work describes the mechanisms of a concept of insulator\u2013semiconductor field-effect devices coupled with nanoplasmonic sensing as a promising technology, which can be used for a wide range of analytical sensing applications. The work\u00a0enables the development of platforms to be used for screening kinase inhibitors, which constitute an important class of chemotherapy drugs,\u00a0and as a dual mode electro-optical biosensor for routine bio\/chemical sensing applications.<\/p>\n
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Nikhil Bhalla<\/span><\/span>, <\/span><\/span>Pedro <\/span>Estrela<\/span><\/span>:<\/span><\/span><\/span><\/p>\n \"Exploiting the signatures of nanoplasmon-exciton coupling on proton sensitive insulator-semiconductor devices for drug discovery applications\"<\/span><\/p>\n