{"id":311,"date":"2018-07-13T12:07:52","date_gmt":"2018-07-13T12:07:52","guid":{"rendered":"http:\/\/blogs.bath.ac.uk\/pmdlce20\/?p=311"},"modified":"2018-07-13T12:08:19","modified_gmt":"2018-07-13T12:08:19","slug":"paper-on-bladder-cancer-diagnosis-using-urine","status":"publish","type":"post","link":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/2018\/07\/13\/paper-on-bladder-cancer-diagnosis-using-urine\/","title":{"rendered":"Paper on bladder cancer diagnosis using urine"},"content":{"rendered":"<p>A novel fluidic-based electrochemical ELISA platform is descried for estimation of the bladder cancer protein markers nuclear mitotic apparatus protein 1 (NUMA1) and complement factor H-related 1 (CFHR1) in urine samples. The platform uses an off-site chamber for a sandwich immunoassay and performs the electrochemistry on-chip in a separate chamber. A fully automated fluidic prototype has also been developed to demonstrate that automation of the process and multiplexing of detection can be achieved in a small footprint benchtop device. The use of off-site matrix-based platforms paves the way towards a new generation of electrochemical immunosensors for biomarker estimation with negligible non-specific interactions and false signals in complex samples.<\/p>\n<p>&nbsp;<\/p>\n<p class=\"Head\"><span class=\"title-text\"><span class=\"content\"><span class=\"text given-name\">Sunil Arya<\/span><\/span><span class=\"content\"><span class=\"text surname\">, <\/span><\/span><span class=\"content\"><span class=\"text given-name\">Pedro <\/span><span class=\"text surname\">Estrela<\/span><\/span><span class=\"content\"><span class=\"text surname\">:<\/span><\/span><\/span><\/p>\n<p class=\"Head\"><span class=\"title-text\">\"Electrochemical ELISA-based platform for bladder cancer protein biomarker detection in urine\"<\/span><\/p>\n<div id=\"banner\" class=\"Banner\">\n<div class=\"wrapper truncated\">\n<div class=\"AuthorGroups\">\n<div id=\"author-group\" class=\"author-group\"><a href=\"https:\/\/doi.org\/10.1016\/j.bios.2018.07.003\" target=\"_blank\" rel=\"noopener\"><strong><em>Biosensors and Bioelectronics<\/em> 117 (2018) 620-627<\/strong><\/a><\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A novel fluidic-based electrochemical ELISA platform is descried for estimation of the bladder cancer protein markers nuclear mitotic apparatus protein 1 (NUMA1) and complement factor H-related 1 (CFHR1) in urine samples. The platform uses an off-site chamber for a sandwich...<\/p>\n","protected":false},"author":117,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[4],"tags":[],"class_list":["post-311","post","type-post","status-publish","format-standard","hentry","category-papers"],"acf":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/posts\/311","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/users\/117"}],"replies":[{"embeddable":true,"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/comments?post=311"}],"version-history":[{"count":0,"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/posts\/311\/revisions"}],"wp:attachment":[{"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/media?parent=311"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/categories?post=311"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/blogs.bath.ac.uk\/pmdlce20\/wp-json\/wp\/v2\/tags?post=311"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}